Designing Inhibitors for Protein-Protein Interactions - Challenges and Approaches

For 15 years, SoftFocus® compound libraries have pioneered the field of rationally designed focused libraries. This webinar discusses approaches to designing libraries targeting protein-protein interactions (PPIs) that predominantly rely on designing scaffolds with the shape, profile and substitution vectors necessary for accurately mimicking protein secondary structure hot-spots or utilizing specific PPIs of interest as the basis for the design of more general PPI libraries.


  • Phillip Black, Sr. Scientist