Dr. Kristen Keefe, a professor of pharmacology and toxicology at the University of Utah, discusses the role of rodent models in assessing a potent CNS stimulant-induced dopamine neurotoxicity, the right models for these studies, and the potential long term consequences of methamphetamine abuse. This video is part of the Researcher's Spotlight, a vlog series which provides a virtual platform for researchers to discuss their work and engage with the broader scientific community.

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Dr. Kristen Keefe, Professor of Pharmacology and Toxicology, College of Pharmacy, University of Utah

Dr. Keefe's laboratory is interested in the structure and function of the basal ganglia, a group of subcortical nuclei in the brain involved in the control of movement and cognition. Her work determines the influence of both endogenous and exogenous chemicals on the function of neurons in the basal ganglia in an attempt to better understand the mechanisms by which drugs of abuse that affect the basal ganglia exert both acute and long-lasting adverse effects. Dr. Keefe received her PhD from the University of Pittsburgh.