This session will discuss assays and strategies to employ UDP-glucuronosyltransferase (UGT) assays for characterization, induction, and inhibition studies. We will present our improved strategy comparing the potential induction of cytochrome P450 (CYP) and UGT between different species using enzyme activity and mRNA analysis as endpoints.

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Jelle Reinen, PhD
Group Leader, In Vitro Drug Metabolism and Pharmacokinetics