Early investigation of solid form characteristics of novel APIs can help identify and mitigate issues while they can still be easily addressed. Understanding the properties of the various crystalline forms a molecule can adopt results in better decisions during lead optimization, leading to identification of more robust development candidates.

In this webinar, the analytical techniques used to evaluate solid forms are reviewed, followed by a case study of a typical polymorphic system, demonstrating the impact of solid form issues on drug discovery programs.

Presenter

  • Andrew Carr, MChem, Pharmaceutics Team Leader, Charles River