Endotoxin testing continues to be an evolving field. Recently, concerns have arisen that endotoxin might not be detected with the LAL assay in many biologics. As part of the continuing conversation around this issue, the webinar discusses:

  • Composition of plasma and endotoxin limits
  • Overcoming LAL interferences
  • An example of low endotoxin recovery (LER), comparing endotoxin reference standard (RSE) with naturally occurring endotoxin (NOE)
  • Successful validation of the LAL assay


  • Claudia Di Paola, Account Manager II, Charles River Microbial Solutions, Italy