Charles River Research Models and Services: University of Pittsburgh and Children's Hospital of Pittsburgh

Charles River is a key provider of research models and services for the University of Pittsburgh and Children's Hospital of Pittsburgh. Our goal is to provide the highest standards of service and quality in everything we do, so your scientists can be empowered to focus on what matters most – your research.

animal technician holding a mouse

Do you have a question or want to brainstorm? Our Technical Sales Specialist, Beth Lotocki, is available to support your needs.

Connect with Beth      Download Your Price List

CHARLES RIVER OFFERS CONTRACT BREEDING & EMBRYOLOGY SERVICES

We have a complete portfolio of embryology services available, including cryopreservation, rederivation, model creation, and rapid colony expansion.

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isolator cages

ACADEMIC WELCOME PROGRAM

Charles River's 2021 Academic Welcome Program is designed to provide new inquiring researchers with special discounts and technical support for their next studies. These program offers are valid through December 31, 2021.

SEE DISCOUNTS
 

researcher holding mouse

PREFERENTIAL PRICING ON CRYOPRESERVATION & REDERIVATION SERVICES

To help protect your unique mouse and rat strains and help ensure research reproducibility, our cryopreservation services have created exclusive limited-time discounts for researchers in academic institutions.

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cryopreservation

OUR ANIMAL MODEL EVALUATION PROGRAM OFFERS ANIMALS AT NO COST

Selecting the appropriate animal model for your studies is critical to the success of your research. Our Animal Model Evaluation Program allows you to assess the quality and compatibility of our animal models before making a commitment. Contact your Technical Sales Specialist, Beth Lotocki, to take advantage of this no-cost program.

CONNECT WITH BETH
 

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GAIN ANIMAL HEALTH INSIGHTS IN JUST 15 MINUTES WITH OUR FAST TRACKS LEARNING SERIES

Are you keeping up with the crucial information you need to protect the health and security of your most crucial research asset – your animal models?

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fast tracks logo

SARS-COV-2 DIAGNOSTIC TESTING AVAILABLE

To support the laboratory animal research community during the global COVID-19 pandemic, our scientists have developed a real-time PCR assay and MFIA COVID-Plex assays that are now available through Charles River's Research Animal Diagnostic Services.

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SAVE UP TO 79% WITH OUR OFFSITE COLONY MANAGEMENT SERVICES

We have calculated your costs for managing 10 cages and compared them with ours. We estimate savings of up to 79% when you choose offsite colony management with Charles River.

SEE YOUR SAVINGS
 

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Introduction to ICM (Internet Colony Management)
Our Internet Colony Management (ICM™) system provides 24-hour access to animal colony data from anywhere in the world. Learn how it can streamline your breeding and colony management workload.

 

Charles River Colony Management Services Offer More than Cost Savings
Are you looking for a cost-saving method of managing your animal colonies? Our off-site housing program allows you not only to reduce your costs, but to gain scientific expertise and digital control of your colony progression.

Benefits

•   Assurance about health status, biosecurity, and genetic integrity
•   Cost saving on animal colony management
•   Advanced data management of colony progression supports complex breeding schemes
•   Researchers are freed to pursue other important research objectives

Why Charles River?

•   Dedicated, knowledgeable project managers
•   Breeding expertise for rodents with all types of mutations
•   24-hour remote access to comprehensive colony management data via ICM™ (Internet Colony Management)
•   Access to embryology, genotyping*, and veterinary services
•   Efficient logistics network and world-wide secure delivery
•   We are a global leader and developer of lab animal diagnostic services

What is Included?

•   Husbandry (water / food / bedding)
•   Weaning / marking / mating / euthanasia / cage moves
•   Packing animals for shipment
•   Veterinary services and recommended care
•   Regular health monitoring in accordance with official guidelines (eg. FELASA)
 

*Ask us if you need genotyping services, PCR-based, or live animal sampling.

The University of Pittsburgh and Children's Hospital of Pittsburgh receive preferential pricing and unique offers for many of our products and services, including:

•   20% discount on all research models including immunodeficient models (excluding specialty and disease models)
•   15% discount on long-distance freight
•   15% discount on standard and Gnoto-safe® shipping crates
•   Special pricing on GEMS and GTS services

Pricing for our NCI catalog offers grantees a reduced price on popular models.
Find out how much you can save

Download our custom catalog using your University of Pittsburgh and Children's Hospital of Pittsburgh email account to view research model discounts and terms and conditions for University of Pittsburgh and Children's Hospital of Pittsburgh. If you have additional questions, contact Beth Lotocki for more information.

Download Price List

Immunodeficient models are important for a variety of research applications. The chart below, showing immunodeficiency and phenotypes, can be used to help identify the model that best fits your research needs. The University of Pittsburgh and Children's Hospital of Pittsburgh receive preferential pricing on many of our immunodeficient models.

Strain
Species
T-Cell-Deficient
B-Cell-Deficient
NK-Cell-Deficient
Hair Coat
RNU Nude Rat YES NO NO NO
Athymic Nude Mouse YES NO NO NO
CD-1® Nude Mouse YES NO NO NO
NU/NU Nude Mouse YES NO NO NO
BALB/c Nude Mouse YES NO NO NO
SCID Hairless Congenic (SHC™) Mouse YES YES NO NO
SCID Hairless Outbred (SHO®) Mouse YES YES NO NO
Fox Chase SCID® Mouse YES YES NO YES
NCI NOD SCID® Beige Mouse YES YES NO YES
Fox Chase SCID® Beige Mouse YES YES Impaired YES
NIH-III Nude Mouse YES YES Impaired NO
NOD SCID Mouse YES YES Impaired YES
NCG Mouse YES YES YES YES

 

Humanized Models
There are several options available if your research requires humanized models, including: 

•   CD34+ Humanized Mouse Model
•   PBMC Humanized Mouse Model
•   NCG/PBMC Select Humanization Kit

Access our NCG Model Capabilities and Applications Brochure to learn more about the benefits of using these specialized models. Researchers at Columbia receive 25% off academic NCG pricing. If you're new to the NCG, ask Beth Lotocki about our evaluation program. 

Xenograft Collection
Our xenograft data collection is designed to help you decide the most appropriate animal model to use when designing a study. To assist you in expediting your model selection process, we have compiled xenograft data on the following models.  
Charles River Oncology Resources
•   Immunodeficient Models Xenograft Data Collection 
•   Immunodeficient Mice
•   Humanized Mice
•   Tumor Model Compendium
Support Your Oncology Studies
The presence of infectious pathogens in research bilogics could introduce variables that potentially impact your resarch, your vivarium, and even your staff. Like quarantine for rodent models, screening for these agents is critical. Please join us for an overview of methods to screen PDX, cell line, antibodies, proteins, and other bilogic materials using semi-quantitative PCR technology. We'll also review prevalence data and the effects that some of the commonly detected infectious agents can have on your research.
Genetically Engineered Models and Services (GEMS) 
Our GEMS division offers a wide variety of services from breeding to model creation. Our decades of experience and vast network of vivariums around the world gives us the opportunity to offer an unparalleled selection of custom models and services to meet your unique needs. Researchers at The University of Pittsburgh and Children's Hospital of Pittsburgh receive many discounts off services provided by GEMS. Use our quoting tool to view the best price for your study.
Model Creation Services
Our experts can guide you through the model creation process.
Breeding Services 
No need to worry about breeding your own colony – we’ll deliver animals to you when you need them. 
Embryology Services
Our embryology services will help you protect your lines and generate new ones. 
•   Our cryopreservation services can protect your lines from genetic drift, natural disasters, and catastrophic events.
•   Rederivation can help you obtain animals that are free of infectious agents.   
•   Rapid colony development uses sophisticated IVF technology to generate animal colonies quickly.
Quarantine Services
Our isolator-based quarantine is ideal for accepting animals into any institution.
Genetic Testing
We offer assay development and genotyping services to maintain the integrity of your lines transgenic lines. 
Surgical Models
Our surgical services are conducted by highly skilled surgeons with vast experience in veterinary medicine and animal science with the ability to perform highly complex catheterizations and cannulations. Our services include:
•   Vascular catheterization
•   Non-vascular catheterizations
•   Cardiovascular surgery
•   Neurological procedures
•   Soft-tissue Procedures
•   Device implants
•   Biospecimens

 

Guidebooks
Check out our free, digital laboratory animal guidebooks on infection surveillance of rodents and colony management for mice and rats in the Charles River Guidebook Series.
Webinars
•   Upcoming
•   On demand
•   GEMS webinars, covering cryopreservation to CRISPR/Cas9 model creation
•   Germ-Free Colony Management
•   Maintaining a Static Microbiome Across Research Projects: Can It Be Done?
•   Immuno-oncology/oncology
•   Continuous Improvements in Humanized Mouse Models
•   Finding the Right Humanized Model for Your Research

Virtual Seminar Topics
Our team of Research Model Specialists offer free educational seminars on a variety of topics, including: 
•   Surgical Models
•   To Breed or Not to Breed
•   NEW: Topics in Health Monitoring
•   Immunodeficient and Humanized Models: Applications for Immuno-Oncology Research
•   Others topics upon request

Posters
•   Common Rodent Health Conditions
•   Metabolic Diseases
•   Immunodeficient Mice
Regulatory Training and Continuing Professional Development
Charles River Insourcing Solutions℠ provides high-quality training and continuing professional development for veterinarians, scientists, lab technicians, and anyone else working in the field of animal research. AALAS-certification classes are available as virtual seminars for professional development, including ALAT, LAT, and LATG.
ARRIVE Guidelines
Read more on ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments), which include clear guidance on research model nomenclature guidelines and other reporting criteria. 

 

How can I get information about special offers on research model and services?
Please contact Technical Sales Specialist, Beth Lotocki
•   Email:     [email protected] 
•   Call/text: 215-801-9168

What is your evaluation program?
Our evaluation program offers free research models to clients that have not used a strain to evaluate the quality and compatibility of our animal models with their research before making a commitment. Whether you have a new research protocol, are conducting or fine-tuning a pilot study, or simply exploring the opportunity to switch to a new animal model, this program can help you make the right choice.
Do you have any COVID-19 related resources? 
Yes. Take a look at our COVID-19 resources. A popular model for work on SARS-CoV-2 is Syrian Hamsters.
Do you have aged models?
Yes. We have readily available aged C57BL/6 mice. For all other models, we provide aging services.
Are health reports available?
Yes. Health reports are available for research animal models bred by Charles River in North America.
Where can I find additional educational resources? 
See our expanded digital resources.
Do you provide information on infectious agents? 
Yes. Understanding infectious agents that can contaminate your research animal facility allows you to develop a plan to manage or prevent an outbreak. Our technical sheets contain information on viruses, bacteria/fungi, and parasites prevalent in laboratory animals.
When can I expect delivery? 
Delivery day for the University of Pittsburgh is Tuesday. 
How do I contact Charles River? 
Please contact our US customer service team directly:
•   Email: [email protected]
•   Phone: 1-800-522-7287