SARS-CoV-2 Diagnostic Testing Available
To support the laboratory animal research community during the global COVID-19 pandemic, our scientists have developed a real-time PCR assay and MFIA COVID-Plex assays that are now available through Charles River's Research Animal Diagnostic Services.
OUR ANIMAL MODEL EVALUATION PROGRAM OFFERS ANIMALS AT NO COST TO YOU
Selecting the appropriate animal model for your studies is critical to the success of your research. Our Animal Model Evaluation Program allows you to assess the quality and compatibility of our animal models before making a commitment. Contact your Technical Sales Specialist, Beth Lotocki, to take advantage of this no-cost program.
CONNECT WITH BETH
IF YOU NEED A HIGHLY IMMUNODEFICIENT MOUSE MODEL...
Our NCG mouse model is the most highly immunodeficient mouse and the model of choice for cancer xenograft modelling, stem cell biology, humanized mice, and infectious disease research.
CHARLES RIVER OFFERS CONTRACT BREEDING & EMBRYOLOGY SERVICES OF GENETICALLY ENGINEERED MICE AND RATS
We have a complete portfolio of embryology services available, including cryopreservation, rederivation, model creation, and rapid colony expansion.
RECEIVE SPECIAL PRICING
Our new quality of service (QOS) tool ensures you receive accurate estimates quickly. You can easily request a quote online for any of your genetically engineered models and service needs – whether it’s for model creation, cryopreservation, or breeding, among others.
Place an Animal Order
We've made it easier than ever to place a research animal model order. Your order will be immediately sent to our customer service team for fulfillment.
Internet Colony Management (ICM)
Our Internet Colony Management (ICM™) system provides 24-hour access for researchers to manage their animal colonies and data. Review real-time data captured cageside and direct action within your colony.
Laboratory Testing Management
LTM™ has been designed to be an easy-to-use system that help you to streamline your sample submission, result reporting and tracking processes for your animal diagnostic needs.
The University of Pittsburgh and Children's Hospital of Pittsburgh receive preferential pricing and unique offers for many of our products and services, including:
• 20% discount on all research models including immunodeficient models (excluding specialty and disease models)
• 15% discount on long-distance freight
• 15% discount on Gnoto-safe® shipping crates
• Special pricing on GEMS and GTS services
Pricing for our NCI catalog offers grantees a reduced price on popular models.
Find out how much you can save
Download our custom catalog using your University of Pittsburgh and Children's Hospital of Pittsburgh email account to view research model discounts and terms and conditions for University of Pittsburgh and Children's Hospital of Pittsburgh. If you have additional questions, contact Beth Lotocki for more information.
Immunodeficient models are important for a variety of research applications. The chart below, showing immunodeficiency and phenotypes, can be used to help identify the model that best fits your research needs. The University of Pittsburgh and Children's Hospital of Pittsburgh receive preferential pricing on many of our immunodeficient models.
|SCID Hairless Congenic (SHC™)||Mouse||YES||YES||NO||NO|
|SCID Hairless Outbred (SHO®)||Mouse||YES||YES||NO||NO|
|Fox Chase SCID®||Mouse||YES||YES||NO||YES|
|NCI NOD SCID® Beige||Mouse||YES||YES||NO||YES|
|Fox Chase SCID® Beige||Mouse||YES||YES||Impaired||YES|
• CD34+ Humanized Mouse Model
Our xenograft data collection is designed to help you decide the most appropriate animal model to use when designing a study. To assist you in expediting your model selection process, we have compiled xenograft data on the following models.
|Charles River Oncology Resources
• Immunodeficient Models Xenograft Data Collection
• Immunodeficient Mice
• Humanized Mice
• Tumor Model Compendium
|Support Your Oncology Studies
The presence of infectious pathogens in research bilogics could introduce variables that potentially impact your resarch, your vivarium, and even your staff. Like quarantine for rodent models, screening for these agents is critical. Please join us for an overview of methods to screen PDX, cell line, antibodies, proteins, and other bilogic materials using semi-quantitative PCR technology. We'll also review prevalence data and the effects that some of the commonly detected infectious agents can have on your research.
|Genetically Engineered Models and Services (GEMS)
Our GEMS division offers a wide variety of services from breeding to model creation. Our decades of experience and vast network of vivariums around the world gives us the opportunity to offer an unparalleled selection of custom models and services to meet your unique needs. Researchers at Columbia receive many discounts off services provided by GEMS. Use our quoting tool to view the best price for your study.
|Model Creation Services
Our experts can guide you through the model creation process.
No need to worry about breeding your own colony – we’ll deliver animals to you when you need them.
Our embryology services will help you protect your lines and generate new ones.
• Our cryopreservation services can protect your lines from genetic drift, natural disasters, and catastrophic events.
• Rederivation can help you obtain animals that are free of infectious agents.
• Rapid colony development uses sophisticated IVF technology to generate animal colonies quickly.
Our isolator-based quarantine is ideal for accepting animals into any institution.
We offer assay development and genotyping services to maintain the integrity of your lines transgenic lines.
Our surgical services are conducted by highly skilled surgeons with vast experience in veterinary medicine and animal science with the ability to perform highly complex catheterizations and cannulations. Our services include:
• Vascular catheterization
• Non-vascular catheterizations
• Cardiovascular surgery
• Neurological procedures
• Soft-tissue Procedures
• Device implants
Check out our free, digital laboratory animal guidebooks on infection surveillance of rodents and colony management for mice and rats.
• Modern Strategies for Infection Surveillance
• Mouse and Rat Colony Management
• On demand
• GEMS webinars, covering cryopreservation to CRISPR/Cas9 model creation
• Germ-Free Colony Management
• Maintaining a Static Microbiome Across Research Projects: Can It Be Done?
• Continuous Improvements in Humanized Mouse Models
• Finding the Right Humanized Model for Your Research
Virtual Seminar Topics
• Common Rodent Health Conditions
• Metabolic Diseases
• Immunodeficient Mice
|Regulatory Training and Continuing Professional Development
Charles River Insourcing Solutions℠ provides high-quality training and continuing professional development for veterinarians, scientists, lab technicians, and anyone else working in the field of animal research. AALAS-certification classes are available as virtual seminars for professional development, including ALAT, LAT, and LATG.
Read more on ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments), which include clear guidance on research model nomenclature guidelines and other reporting criteria.
How can I get information about special offers on research model and services?
|What is your evaluation program?
Our evaluation program offers free research models to clients that have not used a strain to evaluate the quality and compatibility of our animal models with their research before making a commitment. Whether you have a new research protocol, are conducting or fine-tuning a pilot study, or simply exploring the opportunity to switch to a new animal model, this program can help you make the right choice.
|Do you have any COVID-19 related resources?
Yes. Take a look at our COVID-19 resources. A popular model for work on SARS-CoV-2 is Syrian Hamsters.
|Do you have aged models?
Yes. We have readily available aged C57BL/6 mice. For all other models, we provide aging services.
|Are health reports available?
Yes. Health reports are available for research animal models bred by Charles River in North America.
|Where can I find additional educational resources?
See our expanded digital resources.
|Do you provide information on infectious agents?
Yes. Understanding infectious agents that can contaminate your research animal facility allows you to develop a plan to manage or prevent an outbreak. Our technical sheets contain information on viruses, bacteria/fungi, and parasites prevalent in laboratory animals.
|When can I expect delivery?
Delivery day for the University of Pittsburgh is Tuesday.
|How do I contact Charles River?
Please contact our US customer service team directly:
• Email: [email protected]
• Phone: 1-800-522-7287