Genomics Solutions
Applied thoughtfully, genomics services can support all phases of development, from discovery and preclinical studies to translational sciences and clinical sample analyses. When you partner with Charles River, you can expect fast turnaround and actionable results. Our team of experienced scientists use leading edge technologies to deliver high-throughput genomics solutions, from sample preparation to high quality data generation, analysis, and interpretation.
eGuide: Biomarker Solutions from Discovery to Clinical Trials
Learn how strategic biomarker integration can accelerate research & de-risk pipelines to bring life-saving therapies to patients faster. This guide helps you uncover smarter ways to de-risk studies and accelerate timelines, without compromising scientific rigor.
Read the Guide
Nucleic Acids Extraction and QC
High quality nucleic acid extraction, free from inhibitor carry-over contamination, is a crucial prerequisite for downstream genomic applications and solutions. Our teams routinely extract RNA, mRNA, miRNA, and DNA from numerous sources including:
- 60+ animal and human tissues
- Blood and biological fluids
- FFPE samples
- Limited quantities of material
Gene Expression Services
Our comprehensive genomics services offering includes fully integrated gene expression services like NGS sequencing, DNA microarrays, and RT-PCR or multiplex technologies, as well as highly complex data analysis and interpretation in partnership with Fios Genomics.
- RNASeq (Illumina®)
- Affymetrix cartridges and plates, including whole transcriptome arrays and Clariom™ S and D
- miRNA profiling
- NanoString technology
- Gene expression analysis
- RT-qPCR
- Branched DNA technology
- ViewRNA technology
Genotyping Services and Pharmacogenomics
From SNP analysis to genome-wide association studies, Charles River performs scalable genotyping, mutational, and pharmacogenomics analyses.
- Taqman™ assays
- Mutational analyses and tumor mutational burden: targeted sequencing, whole exome sequencing
Data Analysis and Interpretation
To maximize your investment in the generation of accurate, robust data and quality control, we’ve partnered with Fios Genomics to offer you the best genomics solutions and wide range of bioinformatics analysis services to support your drug discovery, preclinical, and clinical research. Applications range from biomarker discovery and characterization, drug repositioning, pathway analysis, predictive toxicology and toxicogenomics, pharmacogenomics, and patient stratification. Our partner’s bioinformatics services will enhance your research with:
- Versatile data transfer to sponsor
- Robust bioinformatics and biostatistics data analysis pipelines
- Analysis of high-dimensional, multi-variant datasets from a variety of high-throughput genomic technology platforms
Genomics services continue to evolve and advance drug development. Partnering with us ensures that you maintain access to the most innovative genomics solutions and the expertise to effectively turn the analysis of your data into action.
Frequently Asked Questions (FAQs) for Genomics Services
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What is Genomics used for?
Genomics refers to the study of the complete set of DNAs and genes within an organism. Some of the main applications and uses of genomics include:
- Disease Research - Identifying genetic contributions to health conditions. This can help develop diagnostic tests, treatments, and cures based on genetic targets.
- Drug Development - Understanding how genetics impacts drug response helps develop targeted therapies and personalized medicine approaches. Pharmacogenomics specifically looks at the relationship between genetics and drug response.
- Rare Disease Diagnosis - Sequencing can identify the genetic cause of rare or undiagnosed diseases.
- Risk Assessment - Assessing individuals' risk for diseases like cancer based on genomic variants. This is used in genetic counseling.
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What is the difference between genomics and genetics?
According to the World Health Organization, the main difference between genomics and genetics is that genetics scrutinizes the functioning and composition of the single gene whereas genomics solutions address all genes and their inter relationships in order to identify their combined influence on the growth and development of the organism.
- How do I get started with your genomics services?
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What is NGS sequencing?
Next generation sequencing (NGS) is a high-throughput method used to determine a portion of the nucleotide sequence of an individual's genome. This technique is part of our genomics services offerings and utilizes DNA sequencing technologies that are capable of processing multiple DNA sequences in parallel.
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Is next generation sequencing for bacterial identification and fungal ID complicated?
We understand that the process of generating and analyzing next generation sequencing for bacterial identification and fungal ID data is challenging, often requiring specialized expertise and software. This can make adoption of in-house NGS daunting, which is why Accugenix has a team of specialists prepared to support you throughout the manufacturing processes.