Fastest Contamination Detection with our ATP Reagents

ATP-bioluminescence, a gold standard rapid detection method, provides an effective approach to confidently detect the presence of microbial contamination in a sample. However, it is dependent upon microbial growth to achieve sufficient levels of ATP for detection. Celsis AMPiScreen® ATP assay kits include reagents that utilize a method of amplifying ATP that is not constrained by the finite amount of metabolic ATP available in the standard bioluminescence assay. The amplification of ATP beyond that which is inherent in the test sample is accomplished through a proprietary reagent, Celsis LuminAMP®, and an additional instrument-controlled amplification period to optimize the detection of microorganisms. 

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Your Guide to Rapid Microbial Detection 
With evolving regulations and increasing production demands, choosing the right rapid method matters. Explore how Celsis® supports confident, compliant microbial detection across product types.
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Sterility in 6 Days, Bioburden in 24 Hours 

Based upon a proven detection method, Celsis AMPiScreen products amplify low levels of contaminant ATP present in a test sample that are then easily detected by bioluminescence in Celsis® instruments. This naturally occurring reaction, which also provides the characteristic glow of fireflies, occurs when the luciferase enzyme converts luciferin into oxyluciferin to produce bioluminescence. This reaction requires the presence of ATP to occur. 

Ready-to-Use ATP Reagents For Rapid Detection 

Our Celsis AMPiScreen ATP assay kit is comprised of three separate ATP reagents, Celsis LuminAMP®, Celsis Luminex®, and Celsis LuminATE®. Each reagent is essentially ready to use off-the-shelf, except for a simple rehydration step of Celsis LuminATE with its included buffer. Reagents are then loaded into the easy access reagent holders on Celsis luminometers. 

  • Celsis AMPiScreen ATP Reagent Features
    • Get results even faster than traditional ATP-based detection
    • Flexible ATP assay kit configuration affords convenient and efficient reagent usage, minimizing waste
    • Simplified reagent preparation; automated reagent injection
    • Compatible on both the Celsis Accel® and Celsis Advance II™ instruments 
  • 400 Assay Kit Configuration
    Product CodeRST400
    400 Assay Kit Configuration*
    • Celsis LuminAMP™  8 x 8.6 mL vials
    • Celsis LuminEX®  8 x 8.6 mL vials
    • Celsis LuminATE®  8 x 50 assay vials
    • Celsis LuminATE® Buffer – 8 x 8.6 mL vials
    Storage Conditions
    • 2 – 8° C
    Shelf Life
    • Up to 12 months at 2 – 8° C

    * Intended for in vitro use only. Safety data sheets (SDS) available upon request.

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Regulatory Changes: USP 73 & 1071 Updates at a Glance
The latest chapters of USP <73> and <1071> introduce key updates impacting sterility testing and rapid microbiological methods (RMMs). Understanding these changes is crucial for compliance and optimizing your microbial testing strategy. Our expert guide breaks down what’s new and how Celsis® can help you stay compliant and efficient.
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