NCG Mouse Model

Triple-immunodeficient models are produced in isolators to provide the high-level biosecurity environment required for animals lacking a normal host defense mechanism. Our NCG mouse is triple-immunodeficient and available for your oncology, immunology, regenerative medicine, and infectious disease research.

Our NCG mouse is triple-immunodeficient and available for your oncology, immunology, regenerative medicine, and infectious disease research. In addition, our new hACE2-NCG mouse is a novel, engineered hACE2-modified mouse developed specifically for COVID-19 research.

Uniquely created using CRISPR-Cas9* technology to alter the Prkdc and Il2rg genes, our NCG mouse is more immunocompromised than commonly used immunodeficient mouse strains, including SCID and nude mice.

*CRISPR/CAS9 used under licenses to granted and pending US and international patents from The Broad Institute and ERS Genomics Limited.