Overview

Once compounds have been synthesized, they undergo purification, rigorous characterization, analysis and structural determinations as required using the latest equipment. Charles River has the capability to perform nuclear magnetic resonance spectroscopy, mass spectrometry, infrared spectroscopy and single-crystal X-ray experiments. High-throughput mass measurements are performed alongside high-throughput LC-MS analysis for structural and chemical purity determinations.

Analytical Chemistry Equipment

  • Waters/Agilent mass-directed autopurification
  • Waters Acquity UPC2 for supercritical fluid chromatography
  • Waters Thar SFC Prep 100 and Investigator systems
  • Waters Thar HT Resolution Analytical SFC-MS
  • Agilent 1200 chiral analytical HPLC
  • Gilson UV directed chiral HPLC purification system
  • High-throughput Acquity UPLC MS systems
  • Micromass Quattro Micro UPLC-MS-MS
  • Agilent 7820 GC plus Agilent 5975 MSD
  • Perkin Elmer SCIEX API5000
  • Waters XEVO QTOF accurate mass MS-MS system
  • Bruker Avance III HD 400 (x2), Avance DPX300, AV400, AVII 400 and Fourier 300 NMR spectrometers¬†