Animal Models of Ophthalmic Diseases
Charles River offers validated disease models that can be used for non-GLP screening studies and more definitive proof-of-concept studies for which we can advise on study designs. We have an extremely low incidence (<0.001%) of adverse complications due to intraocular dosing procedures. Board-certified veterinary ophthalmologists are readily accessible, and we maintain strong industry ties to leading experts in ophthalmology, neurophysiology and surgery.
Routes of Administration for Ocular Medications
- Topical instillation
- Intravitreal/subretinal injections
- Subconjunctival/subtenon injections
- Intracameral injections
- Internal/external implants
- Transplants (corneal)
In addition, we offer supplementary services for your ocular program, including optical coherence tomography (OCT), electroretinography (ERG), tonometry (IOP), digital fundus photography, pachymetry (corneal thickness measurement), vitrectomy, quantitative autoradiography, drug metabolism and enhanced microscopic evaluation.