Endosafe® Customer Service and Order Support

United States

Get support with order processing, price quotations, product information, and shipping inquiries.

Americas: [email protected] | +1.800.762.7016
Europe/Asia/Australia: [email protected] 

International

Endosafe products are available globally through a network of authorized distributors. For a list of regional partners, visit our global locations page.

To place an order outside of the United States, contact [email protected]. 

  • Technical Support for Endotoxin Testing

    For assistance with troubleshooting, method development, or regulatory guidance, contact:

    Email: [email protected]

    United States: 1.800.762.7016
    Northern EU: +353 1 506 9700
    Southern and Central EU: +33 4 37 50 18 91
    Singapore: +65 6742 6007

    Please use the contact information corresponding to your geographic region. 

  • Customer Portal: Documents and Certificates

    The Microbial Solutions Customer Portal provides centralized access to Endosafe documents needed for compliant operations.

    Available:

    • Certificates of Analysis for reagents and accessories
    • Certificates of Quality for accessories
    • Safety Data Sheets
    • Package inserts and kit inserts
    • User guides and operator manuals
    • Warranty forms


    Portal support: [email protected]

    Explore the Portal

  • Software Updates and Regulatory Compliance

    Stay current with validated software to ensure accuracy, data integrity, and FDA 21 CFR Part 11 compliance. 

    • Endosafe® EndoScan-V™ – Version 6.3 introduces enhanced functionality for the Nexus 200™ platform and includes several non-critical bug fixes across other Endosafe instruments. This release is an optional update. Customers may choose whether to install Version 6.3 for both new and existing EndoScan-V installations. Version 6.2.2 remains the primary supported track for most users.
    • Charles River Cortex™ – Current release: Version 1.1.4.
    • Endosafe® nexgen-PTS™ and nexgen-MCS™ Software – Version 11.1.1 remains the standard release for the majority of users. Version 11.2.1 is available to customers operating standalone nexgen-PTS instruments (without EndoScan-V integration) and using the network save function.
    • Endosafe® Nexus™ – Current release: Version 2.7.


    Notes:

    • The Nexus 200 platform operates on EndoScan-V Version 6.2 or higher. Refer to the EndoScan-V section above for details.
    • Use of nexgen software Version 11.1.1 or higher is mandatory when operating Trillium™ recombinant cascade reagent (rCR) cartridge technology. 
  • Software Release Notes

    Endosafe® EndoScan-V™ – Endotoxin Measuring & Analysis Software 

    Version Reference Code Current Release Note Date 
    6.3 RNENDO-ESV63-01 Nov 2025 
    6.2.2 RNENDO-ESV622-08 Oct 2025 
    6.2.1 RNENDO-ESV621-11 Oct 2025 
    6.2 RNENDO-ESV62-12 Oct 2025 
    6.1 RNENDO-ESV61-14 Oct 2025 
    6.0.2 RNENDO-ESV602-12 Aug 2024 
    6.0.1 RNENDO-ESV601-13  Nov 2023 
    6.0 RNENDO-ESV6-11 Nov 2023 
    5.5.5 (SP3) RNENDO-ESV555SP3-11 Aug 2024 

    Charles River Cortex™

    Version Reference Code Current Release Note Date 
    1.1.4 RNENDO-COR114-01 Oct 2025 
    1.1.3 RNENDO-COR113-04 Oct 2025 

    Endosafe® PTS™, MCS™, and nexgen Software 

    Version Reference Code Current Version Release Date 
    11.1.1 RNENDO-NEX1111-06 Oct 2025 
    11.1 RNENDO-NEX111-10 Oct 2025 
    11 RNENDO-NEX11-07 Aug 2025 
    11.01 RNENDO-NEX1101-03 Sep 2024 
    Legacy RNENDO-100712J-00 Apr 2022 

    Endosafe® Nexus™ Software 

    Version Reference Code Current Release Note Date 
    2.7 RNENDO-NEXUS27-01 May 2024 
    2.6.0 (SP1) RNENDO-NEXUS26SP1-04 May 2024 
    2.6.0 RNENDO-NEXUS26-03 Aug 2019 

    Please contact your local representative for release notes and further information. 

  • Endosafe® Product Lifecycle and End-of-Life (EOL) Support

    Endosafe products reach end-of-life when technology advances, standards shift, or regulations change. These transitions help us improve performance, reduce risk, and support compliance. 

    As products approach end-of-support, labs often reassess workflows and equipment. We’re here to guide that process and help teams plan upgrades or replacements. 

    View discontinued Endosafe products and explore next steps here.   

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