Classical rodent models for Parkinson’s disease, such as 6-OHDA or MPTP lesioning, are standard working tools that offer mechanistic support for therapeutic testing. Charles River has extended these tools further by providing a comprehensive and more readily translatable modeling platform of chemically and biologically induced and genetic models.

Animal Models of Parkinson's Disease

  • 6-OHDA Unilateral Intrastriatal Lesion Model
  • 6-OHDA Medial Forebrain Bundle Model
  • MPTP Lesion Model in Mice
  • A53T Alpha-Synuclein Transgenic Mouse Model
  • AAV - Human A53T Transfection Rat Model